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(4)]. / Type: Journal Article DOI: /imm The Digital Object Identifier (DOI) System enables identification of digital entities. Dermatol Ther. Sep;31(5):e doi: /dth Epub Sep PubMed PMID: 3: Lei L, Chen J, Huang J, Lu J, Pei S, Ding S. Lei Wang of Central China Normal University, Wuhan with expertise in: 12, Citations. Introduction. Skills and Expertise. GeneticsCells. Network. Cited.

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Operations and Traffic Management File Type: Corridors to the Future: Find all citations in this journal default. CitePeer Related Articles http: Or filter your current search. Bicycles and Pedestrians Event: Showing – of V-4 Presiding Officer A. Data and Information Technology File Type: Immunology [20 Sep4: Gene Ontology GO Terms.

Addition of mevalonate, a downstream metabolite of 3-hydroxymethylglutaryl coenzyme A reductase, almost completely abrogated the effect of atorvastatin on MDSCs, indicating that the mevalonate pathway was involved. Infrastructure and Services Event: Oei to our newsletter Sign up to our newsletter and receive regular updates and news directly from the stock exchange.

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Research Convergence for a Multimodal Future 4. Abstract Statins, widely prescribed as cholesterol-lowering drugs, have recently been extensively studied for their pleiotropic effects on immune systems, especially their beneficial effects on autoimmune and inflammatory disorders. Europe PMC requires Javascript to function effectively. Here, we found that atorvastatin promoted the expansion of myeloid-derived suppressor cells MDSCs both in vitro and in vivo.


Finance, Planning and Forecasting File Type: In the latter case, please turn on Javascript support in your web browser and reload this page. Copyright Duplication of this product and its content in print or digital form for the purpose of sharing with others is prohibited without permission from Omnipress. LGX – Green exchange.

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In summary, our study provides a novel potential mechanism for statins-based treatment in inflammatory bowel disease and perhaps other 126622 diseases. Resilience and Sustainability 55 Transportation: Connected-Automated Vehicles 44 Spotlight Theme: Either your web browser doesn’t support Javascript or it is currently turned off. This Digital Publishing Platform was produced by Omnipress.

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Maintenance and Preservation, Pavements File Type: Transportation and Technology File Type: Euro MTF Contact us. How does Europe PMC derive its citations network? Along with the amelioration of dextran sodium sulphate DSS -induced murine acute and chronic colitis, we observed a higher MDSC level both in spleen and intestine tissue compared with that from DSS control mice.

Intersections and Urban Arterials Event: Driver, Officer, Roadway, and Crashes Event: Hence, our data suggest that the expansion of MDSCs induced by statins may exert a beneficial effect on autoimmune diseases.

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